Szoptatás és cöliákia

Early infections are associated with increased risk for celiac disease: an incident case-referent study.


BACKGROUND: Celiac disease is defined as a 'chronic small intestinal immune-mediated enteropathy precipitated by exposure to dietary gluten in genetically predisposed individuals'. Sweden has experienced an "epidemic" of celiac disease in children below two years of age. Celiac disease etiology is considered multifactorial; however, little is known regarding potential risk- or protecting factors. We present data on the possible association between early infectious episodes and celiac disease, including their possible contribution to the Swedish celiac disease epidemic.

Timing of introduction of gluten into the infant diet

Scientific Advisory Committee on Nutrition (SACN) and the Committee on Toxicity of Chemicals in Food, Consumer Products and the Environment (COT) Join Statement, March 2011

In 2010, the Department of Health and Food Standards Agency asked the Scientific Advisory Committee on Nutrition (SACN) and the Committee on Toxicity of Chemicals in Food, Consumer Products and the Environment (COT) to assess the evidence on timing of introduction of gluten into the infant diet and subsequent risk of developing coeliac disease or type 1 diabetes mellitus (T1DM). The request was made in response to the publication of a European Food Safety Authority (EFSA) Panel on Dietetic Products, Nutrition and Allergies (NDA) Scientific Opinion on the appropriate age for the introduction of complementary food into infant diets in the EU; this included conclusions that were inconsistent with UK infant feeding advice.

Szakirodalmi összefoglaló és javaslat a glutén szoptatott csecsemők étrendjébe történő bevezetésével kapcsolatban


Az elmúlt hónapokban az egészségügyi dolgozók (gyermekorvosok, védőnők) körében elter­jedt az a nézet, hogy a gluténtartalmú élelmiszereket 4 hónapos korban be kell vezetni a csecsemők étrendjébe, mert a glutén későbbi bevezetése fokozza a cöliákia kialakulásának kockázatát. Ez a javaslat a kutatási eredmények félreértelmezésén alapul, ellentmond az Egészségügyi Világszervezet és az európai egészségügyi szervezetek ajánlásának, és – a szilárd táplálékok túl korai bevezetése miatt – egészségügyi kockázatokat hordoz mind a szoptató anyákra, mind a szoptatott csecsemőkre nézve.

Effect of breast feeding on risk of coeliac disease: a systematic review and meta-analysis of observational studies

A K Akobeng, A V Ramanan, I Buchan and R F Heller

Archives of Disease in Childhood 2006;91:39-43

Background: Coeliac disease (CD) is a disorder that may depend on genetic, immunological, and environmental factors. Recent observational studies suggest that breast feeding may prevent the development of CD.

Aim: To evaluate articles that compared effects of breast feeding on risk of CD.

The Swedish epidemic of coeliac disease explored using an epidemiological approach—some lessons to be learnt

Ivarsson A.

Best Pract Res Clin Gastroenterol. 2005 Jun;19(3):425-40.

Sweden has experienced an epidemic of symptomatic coeliac disease that has no likeness anywhere else in the world. This is quite unique for a disease that is genetically dependent, immune-mediated and chronic, and suggests an abrupt increase and decrease, respectively, of one or a few causal factors influencing a large proportion of Swedish infants during the period in question.

Breast-feeding protects against celiac disease

Anneli Ivarsson, Olle Hernell, Hans Stenlund and Lars Åke Persson
American Journal of Clinical Nutrition, Vol. 75, No. 5, 914-921, May 2002


Background: Celiac disease, or permanent gluten-sensitive enteropathy, is an immunologic disease strictly dependent on exposure to wheat gluten or related proteins in rye and barley.

Objective: The aim of this study was to explore whether breast-feeding and the mode of introducing dietary gluten influence the risk of celiac disease in childhood.

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