Breastfeeding and intelligence: a systematic review and meta-analysis
Horta BL, Loret de Mola C, Victora CG
Acta Paediatr. 2015 Dec;104(467):14-9.
AIM: This study was aimed at systematically reviewing evidence of the association between breastfeeding and performance in intelligence tests.
METHODS: Two independent searches were carried out using Medline, LILACS, SCIELO and Web of Science. Studies restricted to infants and those where estimates were not adjusted for stimulation or interaction at home were excluded. Fixed- and random-effects models were used to pool the effect estimates, and a random-effects regression was used to assess potential sources of heterogeneity.
RESULTS: We included 17 studies with 18 estimates of the relationship between breastfeeding and performance in intelligence tests. In a random-effects model, breastfed subjects achieved a higher IQ [mean difference: 3.44 points (95% confidence interval: 2.30; 4.58)]. We found no evidence of publication bias. Studies that controlled for maternal IQ showed a smaller benefit from breastfeeding [mean difference 2.62 points (95% confidence interval: 1.25; 3.98)]. In the meta-regression, none of the study characteristics explained the heterogeneity among the studies.
CONCLUSION: Breastfeeding is related to improved performance in intelligence tests. A positive effect of breastfeeding on cognition was also observed in a randomised trial. This suggests that the association is causal.
A cikk teljes szövege az Acta Paediatrica oldalán olvasható.