DB Cox, JC Kent, TM Casey, RA Owens, and PE Hartmann
Exp Physiol 1999;84;421-434
Breast volume and morphology of eight subjects were measured before conception and at intervals throughout pregnancy until 1 month of lactation. Breast volume before conception ranged from 293 to 964 ml. At the end of pregnancy the volume of breast tissue had increased by 145+/-19 ml (mean+/-S.E.M., n = 13 breasts, range 12-227 ml) with a further increase to 211+/-16 ml (n = 12 breasts, range 129-320 ml) by 1 month of lactation.
Urinary excretion of lactose increased at 22 weeks of pregnancy, signalling the capacity of the breast to synthesize lactose at this time.
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