Tag Archive for: A laktáció biológiája

Studies in human lactation: milk composition and daily secretion rates of macronutrients in the first year of lactation

JC Allen, RP Keller, P Archer and MC Neville

American Journal of Clinical Nutrition, Vol 54, 69-80

Time-dependent changes in milk composition and secretion from pregnancy through greater than or equal to 6 mo of exclusive breast-feeding were studied in 13 multiparous women. Concentrations and secretion rates of lipid, lactose, protein, sodium, chloride, potassium, total calcium, ionized calcium, magnesium, glucose, citrate, inorganic phosphate, creatinine, and urea and pH were analyzed longitudinally from day 6 until weaning commenced. The composition of the antepartum secretion was related to the permeability of the junctional complexes between mammary cells.

Significant increases in lactose, glucose, pH, and ionized calcium and significant decreases in protein, sodium, potassium, chloride, and calcium concentrations were observed between 1 and 6 mo.
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Peter G. Arthur, Janice Spruce, Peter E. Hartmann, and Trevor J. Jones

Q J Exp Physiol 1989;74;419-428

A Moire contouring method was used to measure changes in the volume of the breast between infant feeds. A tungsten-halogen light source obliquely illuminated the breast through a moving Moire grid to produce contour shadows on the breast. Photographs of the Moire topographs were analysed to obtain three-dimensional co-ordinates of transverse sections through the breast. The cross-sectional areas were calculated using the trapezoidal rule and volumes were calculated by multiplying these areas by their vertical separation.

The precision of the method was found to be dependent on the subject repositioning accurately.
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Effects of different levels of vitamin C intake on the vitamin C concentration in human milk and the vitamin C intakes of breast-fed infants

Lauri 0 Byerley and Avanelle Kirksey
Am J Clin Nutr 1985; 41:665-671.


The influence of maternal intake of vitamin C on the vitamin C concentration in human milk and on the vitamin C intakes of breast-fed infants has not been demonstrated conclusively. This study examined these influences of diet and supplementation in 25 lactating women administered 90 mg of ascorbic acid for 1 day followed by 250, 500 or 1000 mg/day for 2 days or unsupplemented for I day followed by either 0 or 90 mg ascorbic acid supplement for 2 days. Vitamin C content in milk and urine was determined by the 2,4-dinitrophenylhydrazine method.
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Breast Milk Volume and Composition During Late Lactation (7-20 Months)

Dewey, Kathryn G.; Finley, Dorothy A.; Lonnerdal, Bo

Journal of Pediatric Gastroenterology & Nutrition. 3(5):713-720, November 1984.


Breast milk composition of 119 samples collected by 46 women during months 7-20 of lactation was compared with composition of 101 samples collected at 4-6 months. Breast milk intake of 10 infants was determined by test-weighing for 1 or more months during months 7-16 of lactation. Longitudinal decreases in milk concentrations of zinc, copper, and potassium, previously documented for the first 6 months, continued into the second 6 months, while protein, iron, and sodium concentrations showed no further decline. Lactose, fat, calcium, and magnesium concentrations were similar to those in earlier stages of lactation.
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